Tinospora cordifolia, commonly known as Giloy, is a heart-leaved moonseed, also known as Guduchi, and is considered a divine herb. Twenty-four species of an herbaceous vine are found in tropical areas of India, Myanmar, and Sri Lanka, among others. This study aims to comparatively evaluate the influence of host plants Azadirachta indica (Neem), Saraca asoca (Ashoka), Citrus limon (Lemon), and normal giloy (independently growing) based on their phytochemical screening, antioxidant activity, antidiabetic activity, and total flavonoid content. Phytochemical screening reveals the presence of carbohydrates, steroids, glycosides, quinones, phytosterols, flavonoids, proteins, and amino acids. Quantitative estimation revealed that normal T. cordifolia without a host exhibited the highest total flavonoid content. Using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method, the neem-hosted plant shows the highest antioxidant activity, and the neem-hosted giloy and regular giloy showed the highest inhibitory activity in the antidiabetics (α-amylase test). The studies suggest that the host plant affects the bioactive profile of T. cordifolia.

Citrus fruits are potential source of medicinal importance from archaic period. Antimicrobial resistance and side effects of antibiotics is the most common worldwide problem. To minimize these problems, search for novel antimicrobials from natural resources has been increased. The present study was carried out to find out bioactive potential of Citrus cultivars growing invivo and invitro. Leaves, peel, pulp & tissue culture extracts prepared in benzene, ethanol and methanol were screened against four Gram positive, four Gram negative bacteria and two fungal pathogen using agar well diffusion method. Extracts were further analyzed for the minimum inhibitory concentration (MIC).Phytochemical analysis of active extracts showed the presence of alkaloids, glycosides, flavonoids, saponins, steroids, and tannins.