Antibiotics

Over the years, Antibiotics have served in successful treatment of a number of microbial diseases. However in current times, there has been a great increase in resistant microorganisms that have adapted to the previous antibiotics. A World Health Organization report says that antimicrobial resistance is a "major global threat" to human health based on analysis of around 110 countries. The report covers seven pathogenic bacteria which cause common diseases like pneumonia, diarrhea and blood infections. It also emphasized that more antimicrobial compounds need to be discovered and individuals need to help slow the antibiotic resistance process. Drug resistant bacteria has facilitates the requirement of newer antimicrobial agents which can fight against MDR pathogens. Even though around 80% of antibiotics have been discovered and supplied to the Pharmaceutical industries and treated various disease caused by these bacterial pathogens. Present study was done on the primary and secondary screening of actinomycetes from Rhizospheric soil and antibiotics used to treat various diseases caused by MDR organisms. Main study was focussed on isolation and biochemical testing of isolates and extraction of compounds from broth of isolates. Samples taken were from different Rhizospheric regions of Rajasthan.