Rapid industrialization, increased urbanization and improved agricultural production methods have led to an increase in heavy metal pollution in the environment. Weedy Amaranthus species commonly found on roadsides and abandoned lands, such as Amaranthus spinosus were selected for this study. Seedlings of the experimental plants were grown in soil containing USW (Urban Solid Waste) collected from three selected sites in the state of Kerala, India, namely, Vilappilsala, Chavara and Plachimada. Soil parameters such as soil moisture, soil pH, soil organic carbon and alkalinity were estimated. After measuring the initial heavy metal concentrations at the three selected locations, the test plant seedlings were allowed to grow in soil collected from the respective dumpsites for 60 days, and the percentage reduction in heavy metal content was determined. Post-harvest analysis showed a reduction of more than 50% in heavy metal concentration at each site.